Research

PCH2cure: Revealing disease mechanisms underlying the rare neurological disorder pontocerebellar hypoplasia

Funded by Chan Zuckerberg Initiative and the Eva Luise and Horst Köhler Foundation, we are working tightly with clinicians (Prof. Hendrik Rosewich and Prof. Samuel Gröschel, University Hospital Tübingen; Dr. Wibke Janzarik, University Hospital Freiburg) and the German patient organization for PCH, PCH-Familie e.V. (Drs. Julia Matilainen and Axel Lankenau).

Here is the inspiring speech of Dr. Axel Lankenau (PCH-Familie e.V.) at the 2024 CZI Science in Society meeting in San Jose. For details about research initiative PCH2cure, please check out the PCH2cure website. Thanks to the Chan Zuckerberg Initiative for all the support and providing the opportunity to tell such story at the annual Science in Society Meeting.

Enhancing organoid models

Within the Excellence Cluster 3D Matter Made to Order, we are working on improving organoid models through interdisciplinary collaborations with physicists, chemists, engineers, and material scientists.

Mechanisms behind neurotoxicity

In an interdisciplinary project with Dr. Christian Mahringer, University of Stuttgart, we are revealing processes of change induced by a pharmaceutical that disrupts brain development. This project is funded by the Heidelberg Academy of Science and Humanities.